Myskin™ case studies

Patient Profile
Mrs C
82 years old

Medical Condition
Pretibial laceration to right leg.

Before myskin

The Patient
The laceration to Mrs C’s leg was caused by her hitting her leg on a coffee table. The wound did not heal and Mrs C was admitted to hospital for wound debridement and skin closure under general anaesthetic. After surgery the wound deteriorated and despite conventional treatment, remained unhealed for six weeks.

Evaluation
It was decided that myskin would be an appropriate treatment to heal the wound.

For myskin treatment, a thin biopsy (approximately 0.6mm thick, 2cmx2cm) of skin is taken from the thigh area and transported to the laboratory in sterile saline solution. The biopsy is treated with a digestive enzyme overnight. The following day the keratinocytes are isolated from the dermal/epidermal junction, multiplied in cell culture and stored in liquid nitrogen until they are needed.

Three days before dressings are required, keratinocytes are thawed and cultured on a 5cm silicone disc. These discs have a patented surface layer that encourages keratinocytes, to transfer from the dressing to the wound bed and promote re-epithelialization. This cell transfer process takes about four days after which the myskin dressing can be removed and a standard dressing applied.

Wound after seven applications

Outcome
Mrs C was treated weekly with myskin as an inpatient. Healing was noticed after four applications and the wound had completely healed after seven applications of myskin. Mrs C was then discharged home and reviewed in the clinic regularly. After six months the wound had remained healed.

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